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𝐇𝐞𝐚𝐥𝐭𝐡𝐜𝐚𝐫𝐞 𝐀𝐜𝐪𝐮𝐢𝐫𝐞𝐝 𝐈𝐧𝐟𝐞𝐜𝐭𝐢𝐨𝐧𝐬 These are infections that patients acquire during treatment in a healthcare setting, such as a hospital, long-term care facility, or dialysis center. Hospital Acquired Infections (HAI) is the term used by CMS to describe HAIs acquired during certain medical and surgical procedures. These include surgeries of the heart and blood vessels, urinary tract/bladder, gastrointestinal tract, and respiratory system; open-heart surgery; dialysis; and selected skin and wound care procedures. ....#cancer #cancercare #chemocare #cancersymptoms #cancertreatment #chemotherapy #cancercure #cancercells Read more about this topic, in our blog: cancercelltreatment.com/2022/02/17/healthcare-associated-infection/ ... See MoreSee Less

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𝐓𝐡𝐞 𝐅𝐮𝐭𝐮𝐫𝐞 𝐨𝐟 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭𝐬 Targeted therapy is a treatment that uses drugs or other substances to identify and attack specific cancer cells without harming normal cells. Because targeted therapies are designed to hit specific targets on cancer cells, they are often called “targeted therapies”......#cancer #cancercare #chemocare #cancersymptoms #cancertreatment #chemotherapy #cancercure #cancercells cancercelltreatment.com/2022/03/07/cancer-new-paradigm/ ... See MoreSee Less

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𝐌𝐢𝐧𝐞𝐫𝐚𝐥 𝐑𝐞𝐥𝐚𝐭𝐢𝐨𝐧𝐬𝐡𝐢𝐩𝐬 - 𝐕𝐢𝐭𝐚𝐦𝐢𝐧𝐬 - 𝐄𝐧𝐝𝐨𝐜𝐫𝐢𝐧𝐞𝐬 𝐚𝐧𝐝 𝐇𝐞𝐚𝐥𝐭𝐡 Nutrient interrelationships are complex, especially among trace the elements. A mineral cannot be affected without affecting at least two other minerals, each of which will then affect two others, etc. Mineral relationships can be compared to a series of intermeshing gears that are all connected, some directly and some indirectly. .....#cancer #cancercare #chemocare #cancersymptoms #cancertreatment #chemotherapy #cancercure #cancercells ... See MoreSee Less

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Nutrient interrelationships are complex, especially among the trace elements. A mineral cannot be effected without affecting at least two other minerals, each of which will then affect two others, etc.
#cancer #cancercare

https://elements.envato.com/colorful-minerals-rotates-and-pills-fall-down-CNDN737

𝐇𝐨𝐰 𝐦𝐢𝐧𝐝 𝐚𝐟𝐟𝐞𝐜𝐭𝐬 𝐛𝐨𝐝𝐲: 𝘔𝘦𝘯𝘵𝘢𝘭 𝘩𝘦𝘢𝘭𝘵𝘩 𝘪𝘴 𝘢𝘴 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘢𝘴 𝘱𝘩𝘺𝘴𝘪𝘤𝘢𝘭 𝘩𝘦𝘢𝘭𝘵𝘩. #mindfulness
#mindandbody #strongmind
https://cancercelltreatment.com/2022/03/28/sympathetic-stimulation/

𝐂𝐲𝐭𝐨𝐭𝐨𝐱𝐢𝐜 𝘤𝘢𝘯𝘤𝘦𝘳 𝘵𝘳𝘦𝘢𝘵𝘮𝘦𝘯𝘵𝘴 𝘢𝘳𝘦 𝘵𝘩𝘰𝘴𝘦 𝘵𝘩𝘢𝘵 𝘢𝘧𝘧𝘦𝘤𝘵 𝘵𝘩𝘦 𝘤𝘢𝘯𝘤𝘦𝘳 𝘤𝘦𝘭𝘭𝘴 𝘴𝘱𝘦𝘤𝘪𝘧𝘪𝘤𝘢𝘭𝘭𝘺 𝘸𝘪𝘵𝘩𝘰𝘶𝘵 𝘢𝘧𝘧𝘦𝘤𝘵𝘪𝘯𝘨 𝘰𝘵𝘩𝘦𝘳 𝘤𝘦𝘭𝘭𝘴 𝘪𝘯 𝘵𝘩𝘦 𝘣𝘰𝘥𝘺.
#cancer #cancertreatment
https://cancercelltreatment.com/2022/02/27/types-of-cancer-treatment/

Cancer cells have abnormal mutations in their DNA. These mutations allow cancer cells to grow and divide uncontrollably.
#cancer #cancercare #chemocare #cancersymptoms #cancertreatment #chemotherapy #cancercure #cancercells
https://cancercelltreatment.com/2022/04/18/cancer-cell-mutations/

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Interesting Effects of Hypoxia in Cancer

May 10, 2021
Est. Reading: 3 minutes

The Effects of Hypoxia in Cancer

effects of hypoxia

The hypoxia is due to the following mechanism: a decrease in breathable oxygen, reduced or cardiopulmonary failure. The lungs are unable to transfer oxygen from the alveoli to the blood efficiently. If blood oxygen levels are too low, your body may not work correctly. Diseases of the blood, heart, circulation, and lungs may be the most common causes of hypoxia.

A variety of conditions can interfere with the body's ability to send normal oxygen levels to the blood. Still, the hypoxia side effects can be fatal if severe in the short term and can affect the heart or brain if it persists over a long period. Hypoxia or deficient oxygen supply to tissues characterize a series of pathological situations, including cancer.

The hypoxia in cancer is a common feature in solid tumors, contributing locally and systemically to tumor progression. Hypoxia alters cancer cell metabolism and contributes to therapy resistance. As evident in advanced metastatic cancer, a hypoxic environment is often established, which plays an essential role in cancer evolution.

Cancer is a significant public health problem worldwide with few effective treatment choices, poor prognosis, and high mortality rates. The rapid growth of a tumor leads to depletion of its oxygen supply. This results in a reduction in oxygen supply to some regions of the tumor, which is significantly lower than the supply level to healthy tissue.

Hypoxia is due to any condition that reduces or impedes blood circulation in any area of the body. Hypoxia alters cancer cell metabolism and contributes to therapy resistance. Hypoxia side effects generate intratumoral oxygen gradients, contributing to the plasticity and heterogeneity of tumors and promoting a more aggressive and metastatic phenotype.

The rapid growth of tumors means that their increase in size is not accompanied by adequate vascular development, which generates hypoxia within the tumor mass. Due to the insufficient blood supply, these areas are impervious to chemotherapy and ionizing radiation. There are a series of factors that increase or decrease cellular radiosensitivity, O2 being very important since oxygen is the universal radiosensitizer and enhances the action of radiation in all types of cells, which has a very great therapeutic value.

Cancer cells have developed adaptive mechanisms that allow them to survive in these unfavorable conditions. Initial or moderate increase of hypoxia-inducible factor (HIF) α levels could lead to cell adaptation, and in the absence of oxygen, cancer cells adjust to their new microenvironment mainly by angiogenesis stimulation by vascular endothelial growth factor.

Currently, to combat hypoxia, clinical trials are being conducted in which the increase of hemoglobin is promoted, and techniques are used to increase its concentration. Treating both hypoxia and anemia in cancer patients has been shown to result in greater local-regional local-regional tumor control, more prolonged survival, and improved quality of life.

In cancer treatments, it is essential to avoid tumor hypoxia since oxygen is a powerful radio-sensitizer, so preventing or neutralizing it will ensure more significant destruction of the tumor mass. The use of cell-based targeted nanoparticles for effective therapy has been highlighted as a dual-mode treatment strategy to combat drug resistance and improve the efficacy of chemotherapy. Some anticancer drugs targeting HIF have proven successful in slowing or halting tumor growth. Hypoxic prodrugs are activated by cellular reductases, reoxidized into initial drug progenitors in anoxic cells, and converted into cytotoxic substances.

Several proteins have been determined to be over-expressed during hypoxia in cancer cells. Many studies have concluded that HIF-1α, BNIP3, PDK1, and GLUT1 proteins can be used as markers to uncover hypoxia. HIF-1a has been found to stabilize under hypoxia. It then moves to the cell nucleus and increases the transcription rate of genes that control oxygen release, helping the cancerous cells become accustomed to the lack of oxygen. These proteins are considered potential biomarkers of hypoxia and can be recognized with various imaging techniques.

Research is ongoing to discover how this information can be used to develop new forms of therapy and measurement of hypoxia in cancer.

 

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