In healthy states, metal homeostasis is tightly controlled, and its deregulation is implicated as a cause or consequence of many human diseases. The study of trace metals in biology and medicine, historically known as inorganic biochemistry or bioinorganic chemistry, is growing in importance, becoming fashionably known as “metallomics.” (more…)
Skin cancer is the out-of-control growth of abnormal cells in the epidermis, the outermost skin layer, caused by unrepaired DNA damage that triggers mutations. These mutations lead the skin cells to multiply rapidly and form malignant tumors. The main types of skin cancer are basal cell carcinoma (BCC) in the lower part of the epidermis. Squamous cell carcinoma (SCC) are the flat cells that form the surface of the skin. Cutaneous melanoma is cells that make pigments in the skin. Merkel cell carcinoma (MCC) arises from the endocrine (hormonal) cells and nervous systems in the epidermis. Most Dermatologists provide Mohs Surgery or also Chemosurgery. (more…)
What We Do Not Understand About Cancer
In 1761, Giovanni Morgagni of Padua was the first to do something that is now routine; he did autopsies to relate the patient’s illness to pathological findings after death. This research laid the foundation for scientific oncology, the study of cancer. A century later, the development of anesthesia allowed surgery to flourish, and classic cancer operations such as the radical mastectomy were developed. What we do not understand about cancer.
By the middle of the 20th century, researchers found most of the things that caused cancer (carcinogens) cause genetic damage (mutations) that looked a lot like the mutations (more…)
Cationic Zinc What Is It? Numerous zinc supplementation trials have shown that a wide range of health benefits can be realized by increasing the intake of zinc where diets are inadequate in this micronutrient. Zinc ionophores are a chemical species that reversibly binds ions. Zinc ionophores lead to a rapid increase in intracellular zinc levels.
Zinc is a mineral once absorbed in the small intestine by a carrier-mediated mechanism. Once it has been absorbed it becomes Cationic Zinc in the fluids of the body. (more…)