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ðŸ’Ą Did you know cancer was first documented over 2,000 years ago?Despite centuries of research, we still know little about this complex disease. From how cancer cells "go to sleep" to the role of our immune system in tumor growth, these mysteries shape the future of oncology.🔎 Here are 10 fascinating cancer facts that shed light on what we know—and what we don’t.📖 Read more: zurl.co/5z3Kn #CancerAwareness #Oncology #ScienceMatters ... See MoreSee Less
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CLL Cancer: What You Need to Know ðŸĐļ
Chronic Lymphocytic Leukemia (CLL) is a slow-progressing blood cancer that affects the immune system.

Learn more about CLL symptoms, diagnosis, and treatment options here 👇
🔗

#CLL #Leukemia #CancerAwareness

🧎 Cancer is more than one disease—over 100 different types.
From Hippocrates's discovery to modern genetic research, science has come a long way, but many mysteries remain.

🔎 Learn fascinating cancer facts.

📖 Read more:

#Cancer #Oncology #HealthFacts

🔎 Are You Getting Enough #Magnesium?
It plays a crucial role in muscle function, energy production & heart health, yet 80% of people are deficient!

⚠ïļ Deficiency is linked to migraines, fatigue, & heart disease.

📖 Read more →

#Health #Wellness

🧐 What’s the Biggest Cause of Cancer?
Not just genetics—lifestyle, environment, and viruses play a role. Understanding these risks is key to prevention.

🔗 Read more about the hidden culprits behind cancer:

#CancerAwareness #HealthMatters

🚀 Can microgravity help fight cancer?
Scientists aboard the International Space Station study how cancer cells behave in weightlessness.

🔎 Discover the science behind microgravity cancer research:

#CancerResearch #SpaceScience #Microgravity

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Clinical Trials on Animals - Drug Discovery and Development

March 9, 2022
Est. Reading: 4 minutes

Clinical Trials on Animals

The use of clinical trials on animals is an important part of the drug discovery and development process. Animals are used to test the safety and efficacy of new drugs before they are made available to humans. The use of animals in clinical trials helps to ensure that new drugs are safe and effective for human use.

What is a Clinical Trial?

A clinical trial is a research study that is conducted in humans to evaluate the safety and efficacy of new drugs. Clinical trials are conducted in three phases: Phase I, Phase II, and Phase III.

what is a clinical trial

Phase I Clinical Trials

Phase I clinical trials are the first step in the drug discovery process. These trials are used to determine the safety and tolerability of new drugs in humans. Phase I trials are typically conducted in a few healthy volunteers.

Phase II Clinical Trials

Phase II clinical trials are used to determine the efficacy of new drugs in humans. These trials are typically conducted in a larger number of patients who have the disease or condition that the drug is intended to treat.

Phase III Clinical Trials

Phase III clinical trials are used to confirm the safety and efficacy of new drugs in a larger population. These trials are typically conducted in hundreds or thousands of patients who have the disease or condition that the drug is intended to treat.

The cost of clinical trials per patient can range from a few thousand dollars to millions of dollars. The cost of a clinical trial is determined by the size and scope of the trial.

 

Animals Used in Clinical Trials

There are a number of different animal models that can be used in clinical trials. The most common animal model is the mouse. Mice are used to test the safety and efficacy of new drugs for a variety of diseases, including cancer, heart disease, and diabetes. Mice are also used to test the safety and efficacy of new vaccines and gene therapies.

Other animal models that are commonly used in clinical trials include rats, rabbits, and dogs. Rats are used to test the safety and efficacy of new drugs for a variety of diseases, including cancer, heart disease, and diabetes. Rabbits are used to test the safety and efficacy of new vaccines and gene therapies. Dogs are used to test the safety and efficacy of new drugs for a variety of diseases, including cancer, heart disease, and diabetes.

drug testing on animals

Drug testing on animals is an important part of the drug discovery and development process. Animals are used to test the safety and efficacy of new drugs before they are made available to humans. The use of animals in clinical trials helps to ensure that new drugs are safe and effective for human use.

Clinicaltrials.gov is a website maintained by the United States National Library of Medicine that provides information on clinical trials being conducted in the United States and around the world. The website includes information on the purpose of the trial, the age of the patients being recruited, the location of the trial, and contact for more information.

 

Drug discovery has many laws that need to review.

The first law states that researchers must try to use human cells and tissues as much as possible when developing new drugs. The second law forbids any testing of potential cancer cures on humans until the tests have been successfully completed in mice.

The third law is a Clinical Trial Regulation which was created in Europe in order to protect patients who participate in clinical trials. The regulation states that all clinical trials must be registered on a website called Clinicaltrials.gov, and that the results of all clinical trials must be published on the website.

phase i clinical trials

The fourth law is the Animal Welfare Act, which was created in 1966 to ensure the humane treatment of animals used in research. The act requires that researchers must submit a proposal to the National Institutes of Health (NIH) before conducting any research on animals. The proposal must include a description of the proposed research, the justification for the research, and the methods that will be used to minimize pain and distress.

The fifth law is the Food and Drug Administration (FDA) Modernization Act, which was passed in 1997. The act requires the FDA to review all new drugs and medical devices before they can be made available to the public. The act also requires the FDA to approve all new drugs and medical devices before they can be marketed in the United States.

In conclusion, drug discovery and development is a complex process that involves many laws and regulations. The use of animals in clinical trials is an important part of the process and helps to ensure that new drugs are safe and effective for human use. The only way to develop new and innovative drugs is through the use of clinical trials.

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