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What is Carcinogenesis and Cell Transformation in Cancer

March 8, 2022
Est. Reading: 4 minutes

Carcinogenesis Meaning

The process of forming cancer is called carcinogenesis. Cells in your body naturally go through a process of change as they grow and divide. Sometimes this process goes wrong and cells start to grow out of control, creating a tumor.

Every day, your body is exposed to things that can cause changes in the cells of your body, such as radiation, ultraviolet light, and chemicals. Some of these exposures may increase the risk for cancer.

 

Carcinogens

Whats carcinogen? A carcinogen is a substance that can cause cancer. There are many different types of carcinogens, including:

-Radiation: Ionizing radiation, such as X-rays and gamma rays, can damage DNA and cause cancer.

-Ultraviolet light: Ultraviolet light from the sun can damage DNA and cause cancer.

-Chemicals: Carcinogens can be found in many everyday products, including cigarettes, asbestos, and benzene.

-Viruses: Some viruses, such as HPV and hepatitis B virus, can cause cancer by damaging DNA.

 

Carcinogenesis and Oncogenesis

Carcinogenesis and oncogenesis are two different terms that are often used interchangeably. However, there is a difference between the two terms. Carcinogenesis refers to the process by which normal cells are transformed into cancer cells, while oncogenesis refers to the development of cancer. Oncogenesis is the result of carcinogenesis. It is the final stage of the carcinogenic process, and it is when the cancer cells start to grow and spread uncontrollably.

carcinogenesis meaning

Cell Transformation in Cancer

Cancer begins with one or a few abnormal cells. These cells can grow into a tumor if they are not destroyed. The transformation of normal cells into cancer cells is called carcinogenesis. Carcinogenesis is the process by which normal cells are transformed into cancer cells.

Carcinogenesis is a multi-step process that can take many years to complete. It involves the accumulation of genetic damage in cells, which leads to the development of cancer.

The main cause of carcinogenesis is DNA damage. DNA is the genetic material inside cells. It consists of chromosomes, which are made up of DNA molecules. Chromosomes carry the genetic information that determines how a cell behaves.

The types of DNA damage that can lead to cancer include:

-Mutations: Changes in the sequence of DNA molecules

-Deletions: Loss of part of a chromosome

-Duplications: Extra copies of a chromosome

-Inversions: Rearrangement of the order of DNA molecules on a chromosome

-Integrations: Insertion of foreign DNA into chromosomes

 

The Cell Cycle has been intensively studied to help in determining the cause of cancer. This has actually been going on for centuries, from Otto Warburg in the 1920s to a recent publication in 2014 with the new definition of Carcinogenesis, almost 100 years later. So now what?

Carcinogenesis is the origin, production, or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Year Carcinogenesis was introduced: 2014

Cell Transformation as a Neoplastic state is when the cell changes to a non-normal cell that has manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Year Cell Transformation was introduced: 1970 (1968)

Neoplasms are new abnormal growth of tissue. Malignant neoplasms, cancers, show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Year Neoplasms was introduced: 1964-1965

Carcinogenesis Steps

Carcinogenesis is a complex process, and many things can go wrong. The following are some of the most important steps in the process:

-Initiation: The first step in carcinogenesis is the initiation of cancer. This occurs when a cell is exposed to a carcinogen and the damage to its DNA is permanent.

-Promotion: The second step in carcinogenesis is promotion. This occurs when the damaged cells start to divide and grow uncontrollably.

-Progression: The third step in carcinogenesis is progression. This occurs when the cancer cells spread to other parts of the body.

carcinogens

Types of Carcinogenesis

There are two types of carcinogenesis:

-Initiation-promotion: The most common type of carcinogenesis, involves the permanent damage to DNA that leads to the initiation of cancer, followed by promotion and progression.

-Multistage process: This type of carcinogenesis occurs over a long period of time and involves the accumulation of several genetic changes in cells.

The answer today is the same as over 100 years ago, stop the cell transformation.

Cancer is essentially a disease in which cells have lost their normal checks on cell proliferation.

By extension, it may not be surprising that tumor cells, in order to meet the increased requirements of proliferation, often display fundamental changes in pathways of energy metabolism (The Krebs Cycle) and nutrient uptake (Minerals). Otto Warburg, a Nobel Prize winner, first proposed the theory in the 1920s that defects in energy metabolism, particularly in mitochondrial function, may be the root cause of cancer. This theory was largely based on his finding that tumor cells preferentially use glycolysis over mitochondrial oxidative phosphorylation (OXPHOS) for glucose-dependent ATP production even in the presence of ample oxygen to fuel mitochondrial respiration, a phenomenon known as the “Warburg effect” (Warburg 1956)

So, if a natural method delivered by a new science provided a nutrient uptake that enhanced the normal cell and killed the non-normal cell, a solution would be discovered. The CC Treatment works with the immune system, naturally with the help of science, determined by almost a century of study.

Learn More about the CC Treatment

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