Numerous zinc supplementation trials have shown that a wide range of health benefits can be realized by increasing the intake of zinc where diets are inadequate in this micronutrient. Zinc is a mineral once absorbed in the small intestine by a carrier-mediated mechanism. Once it has been absorbed it becomes Cationic Zinc in the fluids of the body.
Zinc is an essential component of a large number (>300) of enzymes participating in the synthesis and degradation of carbohydrates, lipids, proteins, and nucleic acids as well as in the metabolism of other micronutrients. Zinc stabilizes the molecular structure of cellular components and membranes and contributes in this way to the maintenance of cell and organ integrity. Furthermore, zinc has an essential role in polynucleotide transcription and thus in the process of genetic expression. Its involvement in such fundamental activities probably accounts for the essentiality of zinc for all life forms.
Cationic Zinc & Disease
Have you ever searched the relationship between cancer and zinc in PubMed? There are 15,879 publications, that should give some understanding that billions have been spent on research, and understanding the relationship is key for cancer victims and practitioners. Zinc is one of the most important microelements necessary for normal body functioning. Zinc is marked in numerous diseases and, hence, its properties and behavior in the body have long been a subject of extensive study.
If you believe that your zinc levels in your blood provide the entire picture your wrong. Plasma zinc has a rapid turnover rate and it represents only about 0.l percent of total body zinc content. Zinc is required in all body tissues and fluids. If you believe oral zinc supplementation will solve the problem your wrong. Lack of absorbency is the underlying problem.
Dr. Frederic E. Mohs was the developer of the idea of using zinc compositions topically as an anti-skin-cancer agent. In 1933, 23-year-old Frederic E. Mohs was a research assistant assigned to inject different chemicals into cancerous rat tissues to produce specific reactions. Today, the goal of Mohs’ surgery is to completely remove the tumor with maximum preservation of healthy tissue. It seems like now they forget the Zinc.
Cu/Zn Superoxide Dismutase
One of the most common trace-metal imbalances is elevated copper and depressed zinc. The ratio of copper to zinc is clinically more important than the concentration of either of these trace metals. Cu/ZnSOD1 is one of the three human superoxide dismutases identified and characterized in mammals.
When superoxide dismutase is diminished by the imbalance of zinc and copper the damage to cell membranes caused by superoxide radicals is increased.